The clinical endpoint was a reduction in parenteral nutrition of at least 20 percent over baseline measured at week 16 to 24, as a graded response to reductions of recording up to 100 percent.The doses were based on the results of the GATTEX Phase 2 proof-of-concept study where doses were administered of 0.10 and 0.15 mg / kg / d chosen. Because this study had few subjects in the 0.03 mg / kg / d low dose group, it proved the effects the effects of a low dose. Therefore, a small dose of 0.05 mg / kg / d for the for the Phase 3 study. The highest dose did not seem to add value in comparison to the 0.10 mg / kg / d dose, ie 0.10 mg / kg / d dose was defined as the maximum dose for the Phase 3 study selected offer..
In this Phase 3 study, there were no statistically significant differences in the incidence rates of adverse events or serious adverse events between treatment groups compared to placebo.As this study is specific for two communities in Southern California, 50 percent being applicable and relevant for other urban, especially after the last research shows that through 50 percent the population into 10 major cities in Europe live within 150 meters on major road.. Experts Warn Cost Of asthmatic by traffic-related atmospheric pollution is far higher than previous estimates.
‘Notice results suggested costs have been substantially underestimated and steps must be taken in order to reduce the burden of traffic-related air pollution.
A number of of observation and preclinical studies suggested that vitamin D may reduced risk of breast cancer , but the results were contradictory.