Sequential administration of lamivudine with prehistory YMDD mutation should be abandoned.

admin   May 9, 2017   Comments Off on Sequential administration of lamivudine with prehistory YMDD mutation should be abandoned.

The result suggests that lamivudine re – treatment results in patients with pre-exposed lamivudine resistance to a rapid recurrence of YMDD mutation with significant viral rebound and subsequent hepatic failure. Sequential administration of lamivudine with prehistory YMDD mutation should be abandoned.

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